In the summer of 1960, doctors extracted “crimson sludge” from 6-year-old Barbara Lowry’s bones and gave it to her twin.

That surgery, one of the first successful bone marrow transplants, belied the difficulty of the procedure. In the early years of transplantation, scores of patients died as doctors struggled to figure out how to use one person’s cells to treat another. “Cell therapy for blood diseases had a terrifying birth,” Siddhartha Mukherjee writes in his new book, The Song of the Cell.

The transplant story is one of many Mukherjee uses to put human faces and experiences at the heart of medical progress. But what radiates off the pages is the author himself. An oncologist, researcher and Pulitzer Prize–winning author, Mukherjee’s curiosity and wisdom add pep to what, in less dexterous hands, might be dry material. He finds wonder in every facet of cell biology, inspiration in the people working in this field and “spine-tingling awe” in their discoveries.
It’s no surprise that Mukherjee is so seduced by science. This is a man who built a microscope from scratch during the pandemic and has spent years probing biology and its history with luminaries in the field. The Song of the Cell lets readers eavesdrop on these conversations, which can be intimate and enlightening.

On a car ride across the Netherlands, Mukherjee chats with geneticist Paul Nurse, who tells him about the cell division work that ultimately netted Nurse a Nobel Prize (SN: 3/27/21, p. 28). On a walk at Rockefeller University in New York

City, Mukherjee discusses his depression with another Nobel Prize–winning researcher, neuroscientist Paul Greengard. Mukherjee’s vivid imagery lends heft to his feelings. He tells Greengard about experiencing a “soupy fog of grief” after his father’s death and describes “drowning in a tide of sadness.”

In these memories, which Mukherjee uses to segue into the science of depression, and elsewhere in the book, hints of poetry shimmer among the prose. A cell observed under a microscope is “refulgent, glimmering, alive.” A white blood cell’s slow creep is like the “ectoplasmic movement of an alien.” Mukherjee weaves his experiences into the story of cell biology, guiding readers through the lives and discoveries of key figures in the field. We meet the “father of microbiology,” Antonie van Leeuwenhoek, a 17th century cloth merchant who ground globules of Venetian glass into microscope lenses and spied a “marvelous cosmos of a living world” within a raindrop. Mukherjee also teleports us to the present to introduce He Jiankui, the disgraced biophysicist behind the world’s first gene-edited babies (SN: 12/22/18 & 1/5/19, p. 20). Along the way, we also meet Frances Kelsey, the Food and Drug Administration medical officer who refused to approve thalidomide, a drug now known to cause birth defects, for use in the United States, and Lynn Margulis, the evolutionary biologist who argued that mitochondria and other organelles were once free-living bacteria (SN: 8/8/15, p. 22).

Mukherjee traverses a vast landscape of cell biology, and he’s not afraid to pull over and go exploring in the weeds. He describes in detail the flux of ions in nerve cells and introduces a considerable cast of immune system characters. For an even deeper dive, readers can check the footnotes; they are abundant.

What stands out most, though, are Mukherjee’s stories about people: scientists, doctors, patients and himself. As a researcher and a physician, he steps deftly between the scientific and clinical worlds, and, like the microscope he assembled, offers a glimpse into a universe we might not otherwise see.

Mountain lions have no interest in people, or the built-up areas we enjoy. But after a 2018 wildfire in California, local lions took more risks, crossing roads more often and moving around more in the daytime, scientists report October 20 in Current Biology. It’s another way the effects of human development could be putting pressure on vulnerable wildlife — in this case, potentially pushing them toward our bumpers.

The Woolsey Fire began near Los Angeles on November 8, 2018, and burned more than 36,000 hectares in the Santa Monica Mountains. Nearly 300,000 people evacuated, and three people died. Animals fled the fire too, including the local mountain lions (Puma concolor). The fire was a tragedy, but also a scientific opportunity, says Rachel Blakey, a global change biologist at UCLA. Many of the lions wore tracking collars, allowing scientists to study how the fire changed their behavior.
Of the 11 collared cougars in the area at the time, nine made it to safety during the fire itself. “They have really large home ranges, so it’s nothing to them to be able to cover many kilometers in a day,” Blakey says.

No matter how much they moved, the mountain lions avoided people. One collared cat, P-64, initially fled the fire — until he got close to a developed area. Given the choice between fire and people, the lion retreated back into the burning area. “That’s where his movements stopped,” Blakey says. The park service later found P-64’s remains. He’d burned his paws, and it’s possible that he was unable to hunt and starved to death.

Using data from the nine lions that survived the fire and others collared after, the scientists showed that the cats generally avoided the severely burned areas of their territories. With vegetation gone, the cats had little cover for stalking and ambushing prey.

Instead, the cougars stuck to unburned areas, and continued to avoid people. But they took more risks around human infrastructure, increasing their road crossings from an average of about three times per month to five.
These weren’t all two-lane country highways. The first collared lion to successfully cross Interstate 405, which has 10 lanes in places, did it after the Woolsey Fire. And the big cats crossed U.S. Route 101 once every four months, whereas before the fire, they’d crossed only once every two years. Their territories also overlapped more often, increasing the potential for deadly encounters between the solitary cats. And the generally nocturnal animals increased activity during daytime hours from 10 percent to 16 percent of their active time — boosting a lion’s chances of potentially bump into a human.

Road crossing is what Blakey calls a “risk mismatch.” Lions in areas with lots of people appear to weigh the risk of encountering humans as more dangerous. But “running across a freeway is a lot more likely to be fatal,” she says. That risk, combined with the risk of running into other cats, can be deadly. One young, collared male ended up dead on a freeway in the months after the fire. He was fleeing a fight with an older, uncollared male.

Intense burns like the Woolsey Fire highlight the resilience of mountain lions, says Winston Vickers, a wildlife research veterinarian at the University of California, Davis who was not involved in the study. “They have amazing mobility, they mostly can get away from the immediate fire, they mostly survive,” he notes. The changes in risk-taking, he says, could reflect how confined the population is, hemmed into the mountains by human development.

Wildlife crossings, such as the new Wallis Annenberg Wildlife Crossing over the 101, will hopefully give the mountain lions a safer option for roaming, though the main goal is to promote gene flow between lion populations, Blakey says (SN: 5/31/16). In a landscape where fire, humans and highways combine, it’s good to have somewhere to run.

What’s the matter?
The proposed Windchime experiment plans to use only gravity to detect some types of dark matter. Ultrasensitive sensors would be jostled by the gravitational forces of a dark matter “wind” passing by Earth, James R. Riordon reported in “Gravity could aid dark matter search” (SN: 9/10/22, p. 14).

Since dark matter is affected by gravity, reader David Goldberg asked if dark matter orbits the Milky Way’s center just like our solar system does. If the two move together, how would there be a dark matter wind to detect?

It’s possible that dark matter circles the Milky Way’s center at least a little, though it’s hard to say for sure because no one has been able to measure the elusive stuff yet, Riordon says. But to search for dark matter using the Windchime method, it doesn’t really matter whether the mysterious substance moves with the galaxy, he says. That’s because as the sun circles the Milky Way’s center, Earth is also orbiting the sun. Even if the sun happens to move with the same velocity as nearby dark matter, the direction of Earth’s velocity changes over the course of a year, Riordon says. So we should sense the pull of a dark matter wind that shifts with Earth’s seasons.

What’s more, as the planet spins on its axis, the direction of the surface’s movement relative to the galaxy changes throughout the day. “It’s a little like a fish swimming in the ocean,” Riordon says. “Even though the water in general moves with Earth, as a fish swims in various directions, the creature will experience a flow of water relative to its own motion.”

Reader Jack Ryan wondered why, despite its gravitational attraction, dark matter doesn’t form stars, planets and other celestial bodies.

“Because no one knows what dark matter is, we can’t say for certain that it can or cannot form globs or come in very massive particles,” Riordon says. “It’s something that researchers like those on the Windchime team are looking out for.”

For normal matter to create asteroids or planets, it must experience some force beyond gravity, Riordon says. For instance, if two rocks collide in space, electromagnetic forces would prevent them from simply passing through each other. This would then allow gravity to hold the two rocks together. And if the concentration of matter continues to build up, then an asteroid or a planet could eventually form.

Some physicists hope that dark matter experiences other forces, but gravity is currently the only one known to affect it. “If a dark matter particle that only experiences gravity approaches a rock, a planet or another dark matter particle, it would glide right through because there is no force that can stop it,” Riordon says. “Gravity can pull dark matter into a halo, but on its own, it probably can’t stick dark matter together.”
Correction
A line dropped from our feature “Island lessons” (SN: 9/24/22, p. 22). At the end of Page 26, the full sentence should have read: Saban native Dahlia Hassell-Knijff got a degree in biology in Mississippi, then returned to the island, where she oversees projects at the regional Dutch Caribbean Nature Alliance.

In the fall of 2020, the world was staggering under the attack of the SARS-CoV-2 virus. In the United States, more than 4 million cases were reported in November, more than double the number in October. Hospitals were overwhelmed. On the Thursday before Thanksgiving, 1,962 people died.

Now, despite more than 1 million deaths in the United States and more than 6 million worldwide, it’s almost easy to forget that the pandemic’s assault continues. That is, until you hear Belinda Hankins’ story.

Hankins has been diagnosed with long COVID, a collection of symptoms that can include crushing fatigue, brain fog, pain and dizziness and that may affect 1 in 5 people infected with SARS-CoV-2, according to one conservative estimate. She talked with Science News staff writer Meghan Rosen during her appointment at the long COVID clinic at the Johns Hopkins Bayview Medical Center.

“For months we’ve heard estimates about how many people have long COVID,” Rosen told me. “I was interested in going beyond the stats to find out what it’s like for the patients and doctors living with this.”

That effort involved talking with doctors who are trying to figure out how to treat the symptoms of long COVID when the cause is still unknown. And talking with Hankins. “I thought it was extraordinary that [she] let me into her appointment,” Rosen said. “It’s just so generous and so brave.”

I share Rosen’s gratitude. Asking someone in the midst of a life-altering illness to talk with a journalist is a big request. I always worry that people might feel pressure to participate, and I want to be sure that they’ve had time to think through the implications of going public with personal information. Hankins was clear about why she said yes. “She wanted to share her story because a lot of people in her life don’t know what long COVID is and why she’s still so sick,” Rosen said.

In reporting, Rosen brings both her empathy and her serious science chops. She has a Ph.D. in biochemistry and molecular biology and is a graduate of the science journalism program at the University of California, Santa Cruz. She explored careers in biotech but decided that wasn’t the right fit. She wanted to write about health and medicine.

This is actually Rosen’s third stint at Science News: first as an intern, then as a reporter, and now back on the beat after five years of doing communications work for the Howard Hughes Medical Institute. We’re glad she’s back. Not only is she tackling complex issues surrounding COVID-19, including how U.S. public health guidelines affect kids in school (SN Online: 8/19/22), she’s also been sharing her delight in science. That includes stories on genetic variants linked to uncombable hair in children (SN: 10/8/22 & 10/22/22, p. 5); an unusual “snough” call that zoo gorillas appear to have invented to get zookeepers’ attention (SN Online: 8/10/22); and a new robotic pill designed to deliver drugs by scrubbing away mucus in the intestines.

Yes, science is serious and important, but it’s also crazy fun. I don’t think I’m ready to sign up for the robotic intestinal scrub brush, but I sure do enjoy finding out about it.

Across the United States, kids are prepping for back-to-school, or are already in classrooms, and parents are buckling up for another pandemic school year. Like me, many are trying to get a handle on what COVID-19 precautions to take. Updated guidance released last week by the U.S. Centers for Disease Control and Prevention hasn’t exactly helped. It may have made dealing with back-to-school more confusing — and could even spur new outbreaks.

Last November, my fifth grader had to quarantine at home for 10 days after a close contact tested positive. Now, the CDC has nixed the quarantine recommendation for people exposed to COVID-19. Today, our situation could look something like this: My COVID-exposed daughter would mask for 10 days, test on day five, and remain in school the whole time — only the infected child would isolate. That child would stay home for at least five days after a positive test. Then, if the child is fever-free and symptoms are improving, according to the new guidance, they could pop on a mask and hightail it back to class — no testing needed.
That advice could mean more COVID-19 in classrooms. Scientists have shown that people can remain infectious after day five. So without testing for COVID-19, students and teachers won’t know if they’re bringing the disease back to school.

On the same day the CDC’s guidance came out, the U.S. Food and Drug Administration added yet another wrinkle. If you think you’ve been exposed to COVID-19 but test negative with an at-home COVID-19 antigen test, the FDA now recommends testing again … and again. Repeat testing over time cuts the chances you’ll miss an infection and unknowingly spread the virus, the FDA advised on August 11.

It’s hard to say how that advice jibes with the CDC’s new, more-relaxed guidelines. Even the agency has said its public guidance during the pandemic has been “confusing and overwhelming,” the New York Times reports. CDC director Rochelle Walensky is now planning a shake-up that could include restructuring the communications office as well as relying more on preliminary studies rather tha
The CDC’s new guidance has sparked a range of reactions, many negative, among scientists, doctors, parents and teachers. In an informal Twitter poll of Science News followers, roughly 80 percent of the 353 respondents reported that the new CDC guidance made them feel confused, worried or angry and/or exasperated.

Now, it’s up to local school districts to decide what COVID-19 measures to take. “Just because guidance has changed does not mean COVID is gone,” Becky Pringle, president of the National Education Association labor union, said in a statement. Not by a long shot. The United States is currently averaging nearly 500 daily coronavirus deaths and more than 100,000 new cases a day, an almost certain undercount.

As my own children gear up for school, I wonder about COVID-19’s constantly shifting landscape. Like other families with school-aged children, we’ve bounced from virtual school to in-person mask mandates to mask-optional recommendations. And we still don’t know our district’s plans for the upcoming year. School starts in about a week.

There is reason for hope, though: We know what measures can slow COVID-19’s spread in schools. Masking is a big one. A preliminary study posted August 9 linked lifting school mask mandates in Boston-area K–12 schools with a rise in cases among students and staff. At Boston University, mandatory masking plus a vaccine mandate seemed to keep the virus in check in classrooms, scientists reported August 5 in JAMA Network Open. Testing can help, too. A computer analysis from England suggests that regularly rapid testing students can curb classroom transmission, scientists report August 10 in the Royal Society Open Science.
But knowing what works is not the same as actually employing evidence-based measures in the classroom, says Anne Sosin, a public health researcher at Dartmouth College whose research focuses on COVID-19 and rural health equity. She has studied how pandemic policies have impacted schools in northern New England. “I worry that we simply have not seen the political leadership to ensure that all children and educators can safely participate in school.”

I spoke with Sosin about the CDC’s new guidance, and what kids and parents might expect heading into the new school year. Our conversation has been edited for length and clarity.

SN: What do you think of the updated guidance?

Sosin: I was very disappointed that the CDC did not adopt a test-to-exit-isolation recommendation.

What we’re going to see in schools are infected students and educators returning after five days still positive for COVID-19. Multiple studies have demonstrated that most people are infectious beyond five days. Not only is it highly likely that they’ll be seeding outbreaks. They’ll also be putting high-risk members of school communities in danger.

SN: What could the guidance mean for vulnerable kids?

Sosin: I think that vulnerable people are going to be in a very precarious situation. The guidance mentions the need to ensure protections for immunocompromised and other high-risk people but there’s a problem of implementation. Will schools actually implement those protections?

SN: Do scientists have a good handle on what protections can help?

Sosin: Definitely. We have really strong evidence showing that when layered mitigation strategies are in place, we can almost eliminate transmission in school settings. That means that we should have upgraded ventilation, lunchroom strategies [like taking kids outside to eat] and testing. And I continue to think that data-driven mask policies have a role to play. Not masking forever, but masking at times when we see an uptick in transmission.

SN: How could the new guidance affect different communities across the United States?

Sosin: Different communities have not only been impacted in dramatically different ways, but they’re also on unequal footing at this stage of the pandemic.

[If we compare white communities with communities of color], we see disparities in vaccination coverage and caregiver loss. Some communities have suffered enormous losses while others have really been untouched. Black children have lost caregivers at more than two times the rate of white children. For Indigenous children, the rate is 4.5 times as high. Those are sharp disparities.

Communities of color also have less access to testing, treatment and health care. I worry that if we don’t have a renewed focus on equity, then we’re just going to see an exacerbation of disparities that have existed throughout the pandemic.

SN: What advice do you have for parents as they head into the new school year?

Sosin: We all want as normal a school year as possible. Masking should be one of the tools we’re ready to employ to keep our kids in the classroom. In addition, we should be advocating that our schools invest in ventilation. Vaccination also represents a critical piece of the strategy.

We see such abysmal vaccination coverage among children. Less than 1 in 3 kids ages 5 to 11 are fully vaccinated. I think many parents no longer see it as important — there’s been this narrative that the pandemic is over. We need clear messaging that vaccination remains an important tool.

Now is a great time to plan back-to-school campaigns to vaccinate kids and to begin to prepare for the arrival of omicron-specific boosters in the fall.

Archaeologist Peter Bellwood’s academic odyssey wended from England to teaching posts halfway around the world, first in New Zealand and then in Australia. For more than 50 years, he has studied how humans settled islands from Southeast Asia to Polynesia.

So it’s fitting that his new book, a plain-English summary of what’s known and what’s not about the evolution of humans and our ancestors, emphasizes movement. In The Five-Million-Year Odyssey, Bellwood examines a parade of species in the human evolutionary family — he collectively refers to them as hominins, whereas some others (including Science News) use the term hominids (SN: 9/15/21) — and tracks their migrations across land and sea. He marshals evidence indicating that hominids in motion continually shifted the direction of biological and cultural evolution.
Throughout his tour, Bellwood presents his own take on contested topics. But when available evidence leaves a debate unresolved, he says so. Consider the earliest hominids. Species from at least 4.4 million years ago or more whose hominid status is controversial, such as Ardipithecus ramidus, get a brief mention. Bellwood renders no verdict on whether those finds come from early hominids or ancient apes. He focuses instead on African australopithecines, a set of upright but partly apelike species thought to have included populations that evolved into members of our own genus, Homo, around 2.5 million to 3 million years ago. Bellwood hammers home the point that stone-tool making by the last australopithecines, the first Homo groups or both contributed to the evolution of bigger brains in our ancestors.

The action speeds up when Homo erectus becomes the first known hominid to leave Africa, roughly 2 million years ago. Questions remain, Bellwood writes, about how many such migrations occurred and whether this humanlike species reached distant islands such as Flores in Indonesia, perhaps giving rise to small hominids called hobbits, or Homo floresiensis (SN: 3/30/16). What’s clear is that H. erectus groups journeyed across mainland Asia and at least as far as the Indonesian island of Java.

Intercontinental migrations flourished after Homo sapiens debuted, around 300,000 years ago in Africa. Bellwood regards H. sapiens, Neandertals and Denisovans as distinct species that interbred in certain parts of Asia and Europe. He suggests that Neandertals disappeared around 40,000 years ago as they mated with members of more numerous H. sapiens populations, leaving a genetic legacy in people today. But he does not address an opposing argument that different Homo populations at this time, including Neandertals, were too closely related to have been separate species and that it was intermittent mating among these mobile groups that drove the evolution of present-day humans (SN: 6/5/21).

Bellwood gives considerable attention to the rise of food production and domestication in Europe and Asia after around 9,000 years ago. He builds on an argument, derived from his 2004 book First Farmers, that expanding populations of early cultivators migrated to new lands in such great numbers that they spread major language families with them. For instance, farmers in what’s now Turkey spread Indo-European languages into much of Europe sometime after roughly 8,000 years ago, Bellwood contends.

He rejects a recent alternative proposal, based on ancient DNA evidence, that horse-riding herders of Central Asia’s Yamnaya culture brought their traditions and Indo-European tongues to Europe around 5,000 years ago (SN: 11/15/17). Too few Yamnaya immigrated to impose a new language on European communities, Bellwood says. Similarly, he argues, ancient Eurasian conquerors, from Alexander the Great to Roman emperors, couldn’t get speakers of regional languages to adopt new ones spoken by their outnumbered military masters.

Bellwood rounds out his evolutionary odyssey with a reconstruction of how early agricultural populations expanded through East Asia and beyond, to Australia, a string of Pacific islands and the Americas. Between about 4,000 and 750 years ago, for instance, sea-faring farmers spread Austronesian languages from southern China and Taiwan to Madagascar in the west and Polynesia in the east. Precisely how they accomplished that remarkable feat remains a puzzle.

Disappointingly, Bellwood doesn’t weigh in on a recent archaeological argument that ancient societies were more flexible and complex than long assumed (SN: 11/9/21). On the plus side, his evolutionary odyssey moves along at a brisk pace and, like our ancestors, covers a lot of ground.

Sometimes a photo is literally a matter of life, death — and zombies.

This haunting image, winner of the 2022 BMC Ecology and Evolution photography competition, certainly fits that description. It captures the fruiting bodies of a parasitic fungus, emerging from the lifeless body of an infected fly in the Peruvian rainforest.

The fungus-infested fly was one of many images submitted to the contest from all over the world, aiming to showcase the beauty of the natural world and the challenges it faces. The journal revealed the winners August 18.
Roberto García-Roa, a conservation photographer and evolutionary biologist at the University of Valencia in Spain, took the winning photo while visiting the Tambopata National Reserve, a protected habitat in the Amazon.

The fungus erupting from the fly belongs to the genus Ophiocordyceps, a diverse collection of parasitic fungi known as “zombie fungi,” due to their ability to infect insects and control their minds (SN: 7/17/19).

“There is still much to unravel about the diversity of these fungi as it is likely that each insect species infected succumbs to its own, specialized fungus,” says Charissa de Bekker, an expert in parasitic fungi at Utrecht University in the Netherlands.

First, spores of the fungus land on the ill-fated fly. So begins the manipulative endgame. The spores infiltrate the fly’s exoskeleton before infecting its body and eventually hijacking its mind. Once in control, the fungus uses its new powers of locomotion to relocate to a microclimate more suitable to its own growth — somewhere with the right temperature, light and moisture.

Fungus and fly then bide their time until the fly dies, becoming a food source for the fungus to consume. Fruiting bodies work their way out of the fly, filled with spores that are released into the air to continue the macabre cycle in a new, unsuspecting host. It is a “conquest shaped by thousands of years of evolution,” García-Roa said in a statement announcing the winners.

Research into the molecular aspects of fungal mind control is under way, De Bekker says, including in her own lab. “These fungi harbor all sorts of bioactive chemicals that we have yet to characterize and that could have novel medicinal and pest control applications.”

This is the first picture of an exoplanet from the James Webb Space Telescope.

“We’re actually measuring photons from the atmosphere of the planet itself,” says astronomer Sasha Hinkley of the University of Exeter in England. Seeing those particles of light, “to me, that’s very exciting.”

The planet is about seven times the mass of Jupiter and lies more than 100 times farther from its star than Earth sits from the sun, direct observations of exoplanet HIP 65426 b show. It’s also young, about 10 million or 20 million years old, compared with the more than 4-billion-year-old Earth, Hinkley and colleagues report in a study submitted August 31 at arXiv.org.
Those three features — size, distance and youth — made HIP 65426 b relatively easy to see, and so a good planet to test JWST’s observing abilities. And the telescope has once again surpassed astronomers’ expectations (SN: 7/11/22).

“We’ve demonstrated really how powerful JWST is as an instrument for the direct imaging of exoplanets,” says exoplanet astronomer and coauthor Aarynn Carter of the University of California, Santa Cruz.

Astronomers have found more than 5,000 planets orbiting other stars (SN: 3/22/22). But almost all of those planets were detected indirectly, either by the planets tugging on the stars with their gravity or blocking starlight as they cross between the star and a telescope’s view.

To see a planet directly, astronomers have to block out the light from its star and let the planet’s own light shine, a tricky process. It’s been done before, but for only about 20 planets total (SN: 11/13/08; SN: 3/14/13; SN: 7/22/20).

“In every area of exoplanet discovery, nature has been very generous,” says MIT astrophysicist Sara Seager, who was not involved in the JWST discovery. “This is the one area where nature didn’t really come through.”

In 2017, astronomers discovered HIP 65426 b and took a direct image of it using an instrument on the Very Large Telescope in Chile. But because that telescope is on the ground, it can’t see all the light coming from the exoplanet. Earth’s atmosphere absorbs a lot of the planet’s infrared wavelengths — exactly the wavelengths JWST excels at observing. The space telescope observed the planet on July 17 and July 30, capturing its glow in four different infrared wavelengths.

“These are wavelengths of light that we’ve never ever seen exoplanets in before,” Hinkley says. “I’ve literally been waiting for this day for six years. It feels amazing.”

Pictures in these wavelengths will help reveal how planets formed and what their atmospheres are made of.

“Direct imaging is our future,” Seager says. “It’s amazing to see the Webb performing so well.”

While the team has not yet studied the atmosphere of HIP 65426 b in detail, it did report the first spectrum — a measurement of light in a range of wavelengths — of an object orbiting a different star. The spectrum allows a deeper look into the object’s chemistry and atmosphere, astronomer Brittany Miles of UC Santa Cruz and colleagues reported September 1 at arXiv.org.

That object is called VHS 1256 b. It’s as heavy as 20 Jupiters, so it may be more like a transition object between a planet and a star, called a brown dwarf, than a giant planet. JWST found evidence that the amounts of carbon monoxide and methane in the atmosphere of the orb are out of equilibrium. That means the atmosphere is getting mixed up, with winds or currents pulling molecules from lower depths to its top and vice versa. The telescope also saw signs of sand clouds, a common feature in brown dwarf atmospheres (SN: 7/8/22).

“This is probably a violent and turbulent atmosphere that is filled with clouds,” Hinkley says.

HIP 65426 b and VHS 1256 b are unlike anything we see in our solar system. They’re more than three times the distance of Uranus from their stars, which suggests they formed in a totally different way from more familiar planets. In future work, astronomers hope to use JWST to image smaller planets that sit closer to their stars.

“What we’d like to do is get down to study Earths, wouldn’t we? We’d really like to get that first image of an Earth orbiting another star,” Hinkley says. That’s probably out of JWST’s reach — Earth-sized planets are still too small see. But a Saturn? That may be something JWST could focus its sights on. Those three features — size, distance and youth — made HIP 65426 b relatively easy to see, and so a good planet to test JWST’s observing abilities. And the telescope has once again surpassed astronomers’ expectations (SN: 7/11/22).

“We’ve demonstrated really how powerful JWST is as an instrument for the direct imaging of exoplanets,” says exoplanet astronomer and coauthor Aarynn Carter of the University of California, Santa Cruz.

Astronomers have found more than 5,000 planets orbiting other stars (SN: 3/22/22). But almost all of those planets were detected indirectly, either by the planets tugging on the stars with their gravity or blocking starlight as they cross between the star and a telescope’s view.

To see a planet directly, astronomers have to block out the light from its star and let the planet’s own light shine, a tricky process. It’s been done before, but for only about 20 planets total (SN: 11/13/08; SN: 3/14/13; SN: 7/22/20).

“In every area of exoplanet discovery, nature has been very generous,” says MIT astrophysicist Sara Seager, who was not involved in the JWST discovery. “This is the one area where nature didn’t really come through.”

In 2017, astronomers discovered HIP 65426 b and took a direct image of it using an instrument on the Very Large Telescope in Chile. But because that telescope is on the ground, it can’t see all the light coming from the exoplanet. Earth’s atmosphere absorbs a lot of the planet’s infrared wavelengths — exactly the wavelengths JWST excels at observing. The space telescope observed the planet on July 17 and July 30, capturing its glow in four different infrared wavelengths.

“These are wavelengths of light that we’ve never ever seen exoplanets in before,” Hinkley says. “I’ve literally been waiting for this day for six years. It feels amazing.”

Pictures in these wavelengths will help reveal how planets formed and what their atmospheres are made of.

“Direct imaging is our future,” Seager says. “It’s amazing to see the Webb performing so well.”

While the team has not yet studied the atmosphere of HIP 65426 b in detail, it did report the first spectrum — a measurement of light in a range of wavelengths — of an object orbiting a different star. The spectrum allows a deeper look into the object’s chemistry and atmosphere, astronomer Brittany Miles of UC Santa Cruz and colleagues reported September 1 at arXiv.org.

That object is called VHS 1256 b. It’s as heavy as 20 Jupiters, so it may be more like a transition object between a planet and a star, called a brown dwarf, than a giant planet. JWST found evidence that the amounts of carbon monoxide and methane in the atmosphere of the orb are out of equilibrium. That means the atmosphere is getting mixed up, with winds or currents pulling molecules from lower depths to its top and vice versa. The telescope also saw signs of sand clouds, a common feature in brown dwarf atmospheres (SN: 7/8/22).

“This is probably a violent and turbulent atmosphere that is filled with clouds,” Hinkley says.

HIP 65426 b and VHS 1256 b are unlike anything we see in our solar system. They’re more than three times the distance of Uranus from their stars, which suggests they formed in a totally different way from more familiar planets. In future work, astronomers hope to use JWST to image smaller planets that sit closer to their stars.

“What we’d like to do is get down to study Earths, wouldn’t we? We’d really like to get that first image of an Earth orbiting another star,” Hinkley says. That’s probably out of JWST’s reach — Earth-sized planets are still too small see. But a Saturn? That may be something JWST could focus its sights on.

For some ant queens, the secret to long life might be a self-produced insulin blocker.

Ant queens are famously long-lived, even though they shouldn’t be. Generally, animals that put lots of energy into reproduction sacrifice some time off their life. But ant queens produce millions of eggs and live an extraordinarily long time compared with worker ants that don’t reproduce.

Now, researchers have shown how one ant species pulls off this anti-aging feat. When queens and wannabe queens of the species Harpegnathos saltator gear up to reproduce, a part of what’s called the insulin signaling pathway gets blocked, slowing aging, the researchers report in the Sept. 2 Science. That molecular pathway has long been implicated in aging in mammals, including humans.
“There’s been a need to understand why queens, or reproductives, in social insects can live for so amazingly long,” says Marc Tatar, a biologist at Brown University in Providence, R.I., who was not involved with the study. Some ant species have queens that survive 30 times as long as their workers. Other social insects such as bees and termites also have long-lived queens.

In a rare behavior for ants, when a queen H. saltator dies, some female workers begin competing in duels for the chance to replace her (SN: 1/17/14). These hopeful royals develop ovaries, start laying eggs and transition into queenlike forms called gamergates. When a worker transitions to a gamergate, her life span becomes five times as long as it was. But if she doesn’t end up becoming queen and reverts back to a worker, her life span shortens again.

The researchers exploited this behavior to investigate the molecular underpinnings of anti-aging in these ants. H. saltator gamergates, it turns out, extend their life spans by taking advantage of a split in the insulin signaling pathway, the chain of chemical reactions that drive insulin’s effects on the body. One branch of this pathway is involved with reproduction, while the other is implicated in aging.

“Insulin comes with our life — [after] we eat, we have high insulin,” says Hua Yan, a biologist at the University of Florida in Gainesville. “But a constant high level of insulin is bad for longevity.”

Examining patterns of gene activity, Yan and colleagues found that gamergates have more active insulin genes than regular worker ants and, as a result, have increased metabolic activity and ovary development. But the secret sauce protecting the ants from the insulin’s aging effects appears to be a molecule called Imp-L2, which blocks the branch of the insulin pathway linked to aging, experiments showed. The branch involved in reproduction, however, remains active.

“What we don’t understand is how Imp-L2 can act on one aspect of the pathway and not on the other,” says study coauthor Claude Desplan, a developmental biologist at New York University.

These results represent a leap forward in our understanding of extreme social insect longevity, the researchers say, while also showcasing an anti-aging evolutionary adaptation that hasn’t been seen in the wild before.

For some ant queens, the secret to long life might be a self-produced insulin blocker.

Ant queens are famously long-lived, even though they shouldn’t be. Generally, animals that put lots of energy into reproduction sacrifice some time off their life. But ant queens produce millions of eggs and live an extraordinarily long time compared with worker ants that don’t reproduce.

Now, researchers have shown how one ant species pulls off this anti-aging feat. When queens and wannabe queens of the species Harpegnathos saltator gear up to reproduce, a part of what’s called the insulin signaling pathway gets blocked, slowing aging, the researchers report in the Sept. 2 Science. That molecular pathway has long been implicated in aging in mammals, including humans.
“There’s been a need to understand why queens, or reproductives, in social insects can live for so amazingly long,” says Marc Tatar, a biologist at Brown University in Providence, R.I., who was not involved with the study. Some ant species have queens that survive 30 times as long as their workers. Other social insects such as bees and termites also have long-lived queens.

In a rare behavior for ants, when a queen H. saltator dies, some female workers begin competing in duels for the chance to replace her (SN: 1/17/14). These hopeful royals develop ovaries, start laying eggs and transition into queenlike forms called gamergates. When a worker transitions to a gamergate, her life span becomes five times as long as it was. But if she doesn’t end up becoming queen and reverts back to a worker, her life span shortens again.

The researchers exploited this behavior to investigate the molecular underpinnings of anti-aging in these ants. H. saltator gamergates, it turns out, extend their life spans by taking advantage of a split in the insulin signaling pathway, the chain of chemical reactions that drive insulin’s effects on the body. One branch of this pathway is involved with reproduction, while the other is implicated in aging.

“Insulin comes with our life — [after] we eat, we have high insulin,” says Hua Yan, a biologist at the University of Florida in Gainesville. “But a constant high level of insulin is bad for longevity.”

Examining patterns of gene activity, Yan and colleagues found that gamergates have more active insulin genes than regular worker ants and, as a result, have increased metabolic activity and ovary development. But the secret sauce protecting the ants from the insulin’s aging effects appears to be a molecule called Imp-L2, which blocks the branch of the insulin pathway linked to aging, experiments showed. The branch involved in reproduction, however, remains active.

“What we don’t understand is how Imp-L2 can act on one aspect of the pathway and not on the other,” says study coauthor Claude Desplan, a developmental biologist at New York University.

These results represent a leap forward in our understanding of extreme social insect longevity, the researchers say, while also showcasing an anti-aging evolutionary adaptation that hasn’t been seen in the wild before.

Meet the Milky Way in its own words.

The Milky Way: An Autobiography of Our Galaxy takes a tour of our home in the cosmos from an unexpected perspective. Astrophysicist and folklorist Moiya McTier presents herself not as the author, but as the lucky human vessel through which the Milky Way has chosen to tell its story. Then she lets the galaxy take it away, with humor, heart and a huge dose of snark.

The book alternates chapters between science and mythology, reflecting McTier’s dual specialties (her bio says she was the first student in Harvard University’s history to study both). “Many of you don’t realize this, but myths were some of your species’ first attempt at scientific inquiry,” the Milky Way tells us.

The Milky Way is telling its story now because it’s sick of being ignored. Once upon a time, humans looked to the glittering smudge of stars in the sky for insight into when to plant crops or avoid floods. We told stories about the Milky Way’s importance in the origin and fate of the world.

Our galaxy ate it up: For an entity that spends most of its time ripping up smaller galaxies and watching its own stars die, “your stories made me feel loved and needed and, perhaps for the first time in my long existence, more helpful than I was ruinous.” But in the last few centuries, technology and light pollution have pulled humankind away. “At first, I thought it was just a phase,” the Milky Way says. “Then I remembered … that several hundred years is actually a long time for humans.”
So the Milky Way decided to remind us why it’s so important. Its autobiography covers big-picture scientific questions about galaxies, like where they come from (“When a gas cloud loves itself very much,” the Milky Way explains, “it hugs itself extra tight, and after a few hundred million years, a baby galaxy is born. Leave the storks out of it, please.”). It also gets into what galaxies are made of, how they interact with other galaxies, and how they live and die. The book then zooms out to cover the origins and possible ends of the universe, mysteries like dark matter and dark energy, and even humankind’s search for other intelligent life (SN: 8/4/20).

The author takes pains to explain scientific jargon and the technical tools that astronomers use to study the sky. A lot of popular astronomy writing glosses over how astronomers think about cosmic distance or exactly what a spectrum is, but not this book. If you’ve ever been curious about these insider details, The Milky Way has you covered.

McTier’s version of our home galaxy is heavily anthropomorphized. The Milky Way is brash, vain and arrogant in a way that may hide a secret insecurity. Its central black hole is characterized as the physical embodiment of the galaxy’s shame and regrets, a source of deep existential angst. And its relationship with the Andromeda galaxy is like a long-term, long-distance romance, with each galaxy sending stars back and forth as love notes until the two can eventually merge (SN: 3/05/21).

This could have felt gimmicky. But McTier’s efforts to make the metaphors work while keeping the science accurate and up-to-date made the premise endearing and entertaining.

I laughed twice on Page 1. I learned a new word on Page 2. I dog-eared the endnotes early on because it became instantly clear I would want to read every one. I read this book while traveling in rural upstate New York, where the sky is much clearer than at my home outside of Boston. The Milky Way reminded me to look up and appreciate my home in the universe, just like its narrator wanted.